This guide offers organizations information and strategies on building mission effective survivor-defined organizations. It discusses the importance of developing a survivor-defined mission and aligning that mission with the organization’s vision and values, in order to best position the organization to grow and change in ways that make survivors of violence safer. It also explores leadership styles and identifies strategies for promoting reflective practice, critical thinking, participatory management and community engagement as core components of effective leadership. Next, the guide offers tools – including decision-making, strategic planning, and strategic thinking – that promote mission effectiveness and healthy organizational culture. Finally, it connects mission effective leadership and organizations to survivor-defined program development.