Many nonprofit organizations that provide direct human services are exploring how racial equity and inclusion (REI) and performance measurement collectively inform decision-making and strategies that affect their core mission. Human service nonprofits often hold an explicit charge to increase the well-being of people who have been disempowered, disadvantaged, and systematically oppressed. Starting from this mission orientation, organizations can benefit from guidance on operationalizing racial equity values within their measurement and evaluation work and acknowledging the systemic barriers that influence client outcomes.